Inhibits bacterial protein synthesis at the level of the 30S bacterial ribosome.

Therapeutic Effect(s):
Bacteriostatic action against susceptible bacteria.

Spectrum:

• Includes activity against some gram-positive pathogens::

» Bacillus anthracis ,

» Clostridium perfringens ,

» Clostridium tetani ,

» Listeria monocytogenes ,

» Nocardia ,

» Propionibacterium acnes ,

» Actinomyces israelii .

• Active against some gram-negative pathogens::

» Haemophilus influenzae ,

» Legionella pneumophila ,

» Yersinia entercolitica ,

» Yersinia pestis ,

» Neisseria gonorrhoeae ,

» Neisseria meningitidis .

• Also active against several other pathogens, including::

» Mycoplasma ,

» Treponema pallidum ,

» Chlamydia ,

» Rickettsia ,

» B. burgdorferi .