Drug-Drug

• May ↓ metabolism and ↑ risk of toxicity from CYP3A4 substrates , including cyclosporine , HMG-CoA reductase inhibitors , some benzodiazepines ( alprazolam , midazolam , triazolam ), calcium channel blockers , colchicine , fentanyl , tacrolimus , and warfarin .

• .