- High Alert: IV vasoactive medications are inherently dangerous; fatalities have occurred from medication errors involving amiodarone. Before administering, have second practitioner check original order, dose calculations, and infusion pump settings. Patients should be hospitalized and monitored closely during IV therapy and initiation of oral therapy. IV therapy should be administered only by physicians experienced in treating life-threatening arrhythmias.
- Do not confuse amiodarone with amantadine.
- Hypokalemia and hypomagnesemia may decrease effectiveness or cause additional arrhythmias; correct before therapy.
- Monitor closely when converting from IV to oral therapy, especially in geriatric patients.
- PO: May be administered with meals and in divided doses if GI intolerance occurs or if daily dose exceeds 1000 mg.
amiodarone has been found in Davis's Drug Guide
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