• Evaluate for shellfish allergy prior to initiating therapy

• Monitor pain (type, location, and intensity) and range of motion on an ongoing basis as an indicator of drug efficacy

• Assess glucose levels via home monitoring device for patients with diabetes until response is ascertained

• Evaluate gastric discomfort and instruct patient to seek out the advice of a health care provider if persistent gastric discomfort occurs

• Assess bowel function and symptomatically treat constipation with improved fluid intake and bulk in diet and bulk laxatives if necessary