Absorption: Minimal systemic absorption.
Distribution: Action is local, within the GI tract.
Protein Binding: Minimally absorbed drug is >99% bound to plasma proteins.
Metabolism and Excretion: Major route is fecal elimination of unabsorbed drug.
Half-life: 12 hr.
TIME/ACTION PROFILE (effects on fecal fat)
|PO||2448 hr||unknown||4872 hr|
orlistat has been found in Davis's Drug Guide
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