Nursing Central: lovastatin

lovastatin

Route/Dosage

• PO (Adults): 20 mg once daily with evening meal. May be ↑ at 4-wk intervals to a maximum of 80 mg/day (immediate-release) or 60 mg/day (extended-release); initiate at 10 mg/day in patients receiving cyclosporine or other immunosuppressants and do not exceed 20 mg/day; should not exceed 40 mg/day (immediate-release) or 20 mg/day (extended-release) if receiving verapamil or amiodarone; should not exceed 20 mg/day if receiving danazol or niacin (>1 g/day)..

Renal Impairment

• PO (Adults): CCr <30 mL/min—dosage should not exceed 20 mg/day unless carefully titrated..

• PO (Children /Adolescents 10-17 yr): Familial heterozygous hypercholesterolemia—10-40 mg/day; adjusted at 4 wk intervals..

lovastatin has been found in Davis's Drug Guide

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