- Drugs and substances that may decrease the MCHC include styrene (occupational exposure).
- Drugs that may decrease the MCV include nitrofurantoin.
- Drugs that may increase the MCV include colchicine, pentamidine, pyrimethamine, and triamterene.
- Drugs that may increase the MCH and MCHC include oral contraceptives (long-term use).
- Diseases that cause agglutination of RBCs will alter test results.
- Cold agglutinins may falsely increase the MCV and decrease the RBC count. This can be corrected by warming the blood or diluting the sample with warmed saline and then correcting the RBC count mathematically.
- RBC counts can vary depending on the patient’s position, decreasing when the patient is recumbent as a result of hemodilution and increasing when the patient rises as a result of hemoconcentration.
- Care should be taken in evaluating the CBC after transfusion.
- Venous stasis can falsely elevate RBC counts; therefore, the tourniquet should not be left on the arm for longer than 60 sec.
- Failure to fill the tube sufficiently (i.e., tube less than three-quarters full) may yield inadequate sample volume for automated analyzers and may be a reason for specimen rejection.
- Hemolyzed or clotted specimens should be rejected.
- Lipemia will falsely increase the hemoglobin measurement, also affecting the MCV and MCH.
Complete Blood Count, RBC Indices has been found in Davis's Lab & Diagnostic Tests
If you are a registered user, please login below.
If not, learn more about gaining full access.
- Try and Buy
- Nursing Central puts five fully integrated references at your fingertips on mobile devices and the web. See how Nursing Central works by clicking the sample entries below or purchase a subscription for the web and your mobile device.
View these free topics online now.