Antinuclear antibodies (ANA), anti-DNA (anti-ds DNA), antiextractable nuclear antigens (anti-ENA, ribonucleoprotein [RNP], Smith [Sm], SS-A/Ro, SS-B/La), anti-Jo (antihistidyl transfer RNA [tRNA] synthase), and antiscleroderma (progressive systemic sclerosis [PSS] antibody, Scl-70 antibody, topoisomerase I antibody).
To diagnose multiple systemic autoimmune disorders; primarily used for diagnosing systemic lupus erythematosus (SLE).
Serum (3 mL) collected in a red-top tube.
(Method: Indirect fluorescent antibody for ANA and anticentromere; Immunoassay multiplex flow for anti-DNA, ENA, Scl-70, and Jo-1).
ANA and anticentromere: Titer of 1:40 or less. Anti-ENA, Jo-1, and anti-Scl-70: Negative. Reference ranges for anti-DNA, anti-ENA, anti-Scl-70, and anti-Jo-1 vary widely due to differences in methods and the testing laboratory should be consulted directly.
|Negative||Less than 5 international units|
|Indeterminate||5–9 international units|
|Positive||Greater than 9 international units|
Antibodies, Antinuclear, Anti-DNA, Anticentromere, Antiextractable Nuclear Antigen, Anti-Jo, and Antiscleroderma has been found in Davis's Lab & Diagnostic Tests
If you are a registered user, please login below.
If not, learn more about gaining full access.
- Try and Buy
- Nursing Central puts five fully integrated references at your fingertips on mobile devices and the web. See how Nursing Central works by clicking the sample entries below or purchase a subscription for the web and your mobile device.
View these free topics online now.