GENDER, ETHNIC/RACIAL, AND LIFE SPAN CONSIDERATIONS
The incidence of gallbladder disease increases with age. Most patients are middle-aged or older women, often women who have borne several children and gained weight during the aging process. Since there is a tendency for gallbladder disease to be familial, some young people of both sexes with a familial history as well as young women who have taken oral contraceptives can be affected. Risk factors include obesity; middle age; female gender; and Northern European, Native American, or Hispanic/Latino ancestry. Prevalence of gallstones is low in African Americans; however, African Americans with sickle cell disease may have gallstones at a younger age than other populations.
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