ocular hypotensive agent
Lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Acts as a prostaglandin analogues that decreases intraocular pressure by ↑ uveoscleral outflow.
↓ intraocular pressure.
Absorption: Absorbed through cornea and is converted to the active metabolite tafluprost acid.
Metabolism and Excretion: Further metabolized and eliminated.
TIME/ACTION PROFILE (↓ in intraocular pressure)
|Ophth||within 2–4 hr||12 hr||24 hr|
Use Cautiously in:
EENT: conjunctival hyperemia, blurred vision, cataract, permanent iris pigmentation, eyelid pigmentation, lash pigmentation/increased thickness/↑ number, macular edema, ocular stinging/irritation
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Ophth: (Adults): One drop once daily (into conjunctival sac) in the evening into affected eye(s).
Ophthalmic solution : 0.0015% in 0.3 mL single-use containers
Wash hands prior to instillation. Pull lower lid downward and look up. Instill 1 drop in conjunctival sac each evening. Each unit is for one-time use; discard after using. Store unopened foil pouches in refrigerator. Do not open pouch until ready to use.
Reduction of intraocular pressure.
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