Ocriplasmin must be administered by a qualified physician.
Intravitreal Remove vial from freezer and allow to thaw for few min at room temperature. Solution is clear and colorless without particles; do not administer solutions that are discolored or contain particulate matter. Withdraw all solution from vial with a 19 gauge needle. Replace needle with 30 gauge needle and expel excess air and solution to 0.1 mL. Discard unused solution. Administer adequate anesthesia and a broad spectrum antibiotic as per protocol. Intravitreal injection is done via aseptic technique. Repeat administration in same eye is not recommended.
Wait 7 days before treating other eye if necessary.
Explain procedure for intravitreal injection to patient.
Advise patient to notify health care professional immediately if signs and symptoms of intraocular inflammation/infection (eye redness, sensitivity to light, eye pain, change in vision) occurs.
May cause visual changes. Advise patient to avoid driving and other activities requiring good vision until response to medication is known.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Improved vision in patients with vitreomacular adhesions.
ocriplasmin is a sample topic from the Davis's Drug Guide.
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