Lactate Dehydrogenase and Isoenzymes
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Synonym/Acronym:
LDH and isos, LD, and isos.
Rationale
To assess myocardial or skeletal muscle damage toward diagnosing disorders such as myocardial infarction or damage to brain, liver, kidneys, and skeletal muscle.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
(Method: Enzymatic [L to P] for lactate dehydrogenase, electrophoretic analysis for isoenzymes) Reference ranges are method dependent and may vary among laboratories.
| Age | Conventional and SI Units |
|---|---|
| 0–2 yr | 125–275 units/L |
| 2–3 yr | 166–232 units/L |
| 4–6 yr | 104–206 units/L |
| 7–12 yr | 90–203 units/L |
| 13–14 yr | 90–199 units/L |
| 15–43 yr | 90–156 units/L |
| Greater than 43 yr | 90–176 units/L |
| LDH Fraction | % of Total | Fraction of Total |
|---|---|---|
| LDH1 | 14–26 | 0.14–0.26 |
| LDH2 | 29–39 | 0.29–0.39 |
| LDH3 | 20–26 | 0.2–0.26 |
| LDH4 | 8–16 | 0.08–0.16 |
| LDH5 | 6–16 | 0.06–0.16 |
Critical Findings and Potential Interventions
N/A
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Synonym/Acronym:
LDH and isos, LD, and isos.
Rationale
To assess myocardial or skeletal muscle damage toward diagnosing disorders such as myocardial infarction or damage to brain, liver, kidneys, and skeletal muscle.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
(Method: Enzymatic [L to P] for lactate dehydrogenase, electrophoretic analysis for isoenzymes) Reference ranges are method dependent and may vary among laboratories.
| Age | Conventional and SI Units |
|---|---|
| 0–2 yr | 125–275 units/L |
| 2–3 yr | 166–232 units/L |
| 4–6 yr | 104–206 units/L |
| 7–12 yr | 90–203 units/L |
| 13–14 yr | 90–199 units/L |
| 15–43 yr | 90–156 units/L |
| Greater than 43 yr | 90–176 units/L |
| LDH Fraction | % of Total | Fraction of Total |
|---|---|---|
| LDH1 | 14–26 | 0.14–0.26 |
| LDH2 | 29–39 | 0.29–0.39 |
| LDH3 | 20–26 | 0.2–0.26 |
| LDH4 | 8–16 | 0.08–0.16 |
| LDH5 | 6–16 | 0.06–0.16 |
Critical Findings and Potential Interventions
N/A
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