Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.
- Angelica sinensis
- Chinese Angelica
- Dang Gui
- Don Quai
- Radix angelicae gigantis
- Tang Kuei
- Tan Kue Bai Zhi
- Premenstrual syndrome
- Various uses as a blood purifier
- Topically in combination with other ingredients for premature ejaculation
- May have vasodilating and antispasmodic properties.
- Binds to estrogen receptors.
Improved ejaculatory latency.
Metabolism and Excretion: Unknown.
- Allergy to carrot, celery, mugwort, or other members of the Apiaceae family;
- OB: Pregnancy and lactation.
Use Cautiously in:
- Hormone sensitive cancers and conditions (may exacerbate effects or stimulate growth of cancer cells);
- Protein S deficiency (↑ risk for thrombosis);
- Surgery (discontinue 2 wk prior to procedure).
Adverse Reactions/Side Effects
Misc: Some constituents are carcinogenic and mutagenic
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Natural Drug Interaction
- Alcohol-containing preparations may interact with disulfiram and metronidazole.
- Use of dong quai with anticoagulant and antiplatelet drugs, thrombolytics, NSAIDs, some cephalosporins, and valproates may increase risk of bleeding.
PO (Adults) Bulk herb–3–4.5 g per day in divided doses with meals; Extract–1 mL (20–40 drops) three times daily.
Bulk herb: OTC
- Assess pain and menstrual patterns prior to and following menstrual cycle to determine effectiveness of this herbal supplement.
- Assess for pregnancy prior to recommending use of the herbal supplement and warn women not to take this herb if pregnancy is planned or suspected.
- Assess for history of hormone sensitive cancers or conditions and warn against use.
- Assess medication profile including prescription and over-the-counter use of products such as aspirin- and ibuprofen-based products to treat menstrual pain.
- Acute pain (Indications)
- Deficient knowledge, related to medication regimen (Patient/Family/Teaching)
- PO Take with meals.
- Warn patients not to take this medication if pregnant or breast feeding.
- Inform patients to avoid use of aspirin or other NSAIDs concurrently because of the risk of bleeding.
- Notify patients that there are no studies supporting the use of this herbal supplement for treatment of menopausal symptoms.
- Tell patients to consult their health care professional if taking prescription medications before taking dong quai.
- Discontinue the herbal supplement if diarrhea or excessive bleeding occurs and contact a health care provider if symptoms do not resolve.
- Instruct patients that photosensitivity may occur and to wear sunscreen and protective clothing if sun exposure is anticipated.
Reduction in menstrual pain and cramping and regular periods with normal flow.
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