Gastrin and Gastrin Stimulation Test

Gastrin and Gastrin Stimulation Test is a topic covered in the Davis's Lab & Diagnostic Tests.

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To evaluate gastric production to assist in diagnosis of gastric disease such as Zollinger-Ellison syndrome and gastric cancer.

Patient Preparation
There are no fluid or activity restrictions unless by medical direction. Instruct the patient to fast for 12 hr before the test. Instruct the patient to refrain from the use of chewing gum or tobacco products for at least 4 hr prior to and for the duration of the test. Instruct the patient to withhold medications and alcohol for 12 to 24 hr, as ordered by the health-care provider (HCP). Protocols may vary among facilities.

Normal Findings
Method: Immunoassay.

AgeConventional UnitsSI Units (Conventional Units × 0.481)
ChildLess than 65 pg/mLLess than 31 pmol/L
AdultLess than 100 pg/mLLess than 48.1 pmol/L
Values represent fasting levels.
Stimulation Tests
Gastrin stimulation test with secretin; 0.4 mcg/kg by IV bolusNo response or slight increase over baseline; increase of greater than 200 pg/ml (SI units: 96 pmol/L) above baseline is considered abnormal
Calcium may also be used as a stimulant.

Critical Findings and Potential Interventions

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