Plasminogen
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General
Synonym/Acronym:
Profibrinolysin, PMG.
Common Use:
To assess thrombolytic disorders such as disseminated intravascular coagulation (DIC) and monitor thrombolytic therapy.
Specimen:
Plasma collected in a completely filled blue-top (3.2% sodium citrate) tube. If the patient’s hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted.
Normal Findings:
(Method: Chromogenic substrate for plasminogen activity and nephelometric for plasminogen antigen)
| Plasminogen activity | 80%–100% of normal | ||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Plasminogen antigen | 7.5–15.5 mg/dL | ||||||||||||||||||||||||||||||||||||||||
| Plasminogen activity in newborns is half of adult ranges. | |||||||||||||||||||||||||||||||||||||||||
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