Testosterone, Total and Free

Testosterone, Total and Free is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
N/A

Rationale
To evaluate testosterone to assist in identification of disorders related to early puberty, late puberty, and infertility while assessing gonadal and adrenal function.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: HPLC/tandem MS for total and immunochemiluminometric assay (ICMA) for free testosterone.


Total Testosterone
AgeConventional UnitsSI Units (Conventional Units × 0.0347)
Newborn
 Male75–400 ng/dL2.6–13.9 nmol/L
 Female16–44 ng/dL0.56–1.53 nmol/L
1–5 mo
 MaleLess than 300 ng/dLLess than 10.41 nmol/L
 FemaleLess than 20 ng/dLLess than 0.69 nmol/L
6–11 mo
 MaleLess than 40 ng/dLLess than 1.39 nmol/L
 FemaleLess than 9 ng/dLLess than 0.31 nmol/L
1–5 yr
 Male and femaleLess than 20 ng/dLLess than 0.69 nmol/L
6–7 yr
 MaleLess than 20 ng/dLLess than 0.69 nmol/L
 FemaleLess than 10 ng/dLLess than 0.35 nmol/L
8–10 yr
 Male2–25 ng/dL0.07–0.87 nmol/L
 Female1–30 ng/dL0.04–1 nmol/L
11–12 yr
 MaleLess than 350 ng/dLLess than 12.1 nmol/L
 FemaleLess than 50 ng/dLLess than 1.74 nmol/L
13–15 yr
 Male15–500 ng/dL0.52–17.35 nmol/L
 FemaleLess than 50 ng/dLLess than 1.74 nmol/L
Adult
 Male241–827 ng/dL8.36–28.7 nmol/L
 Female15–70 ng/dL0.52–2.43 nmol/L
Older adult
 Male300–720 ng/dL10.41–24.98
 Female5–32 ng/dL0.17–1.11
Post menopausal levels are about half the normal adult level for females; levels in women who are pregnant are three to four times the normal adult level for females who are not pregnant.

Free Testosterone
AgeConventional UnitsSI Units (Conventional Units × 3.47)
1–12 yr
 Male and femaleLess than 2 pg/mLLess than 6.94 pmol/L
12–14 yr
 MaleLess than 60 pg/mLLess than 208 pmol/L
 FemaleLess than 2 pg/mLLess than 6.94 pmol/L
14–18 yr
 Male4–100 pg/mL13.88–347 pmol/L
 FemaleLess than 10 pg/mLLess than 34.7 pmol/L
Adult
 Male50–224 pg/mL173.5–777.28 pmol/L
 Female1–8.5 pg/mL3.47–29.5 pmol/L
Older adult
 Male5–75 pg/mL17.35–260.25 pmol/L
 Female1–8.5 pg/mL3.47–29.5 pmol/L

Critical Findings and Potential Interventions
N/A

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