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Porphyrins, Urine

Porphyrins, Urine is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
Coproporphyrin, porphobilinogen, urobilinogen, and other porphyrins.

Common Use:
To assess for porphyrins in the urine to assist with diagnosis of genetic disorders associated with porphyrin synthesis as well as heavy metal toxicity.

Specimen:
Urine from a random or timed specimen collected in a clean, amber-colored plastic collection container with sodium carbonate as a preservative.

Normal Findings:
(Method: High-performance liquid chromatography for porphyrins; spectrophotometry for δ-aminolevulinic acid and porphobilinogen)

TestConventional UnitsSI Units
(Conventional units × 1.53)
Coproporphyrin I0–24 mcg/24 h0–36.7 nmol/24 hr
Coproporphyrin III0–74 mcg/24 hr0–113.2 nmol/24 hr
(Conventional units × 1.43)
Uroporphyrins0–24 mcg/24 hr0–34.3 nmol/24 hr
(Conventional units × 1.34)
HexacarboxylporphyrinLess than 1 mcg/24 hrLess than 1.34 nmol/24 hr
(Conventional units × 1.27)
HeptacarboxylporphyrinLess than 4 mcg/24 hrLess than 5.1 nmol/24 hr
(Conventional units × 4.42)
PorphobilinogenLess than 2 mg/24 hrLess than 8.8 micromol/24 hr
(Conventional units × 7.626)
δ-Aminolevulinic acid1.5–7.5 mg/24 hr11.4–57.2 micromol/24 hr

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Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Porphyrins, Urine." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425047/all/Porphyrins__Urine.
Bladh ML, Van Leeuwen AM. Porphyrins, Urine. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425047/all/Porphyrins__Urine. Accessed April 24, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Porphyrins, Urine. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425047/all/Porphyrins__Urine
Bladh ML, Van Leeuwen AM. Porphyrins, Urine [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 April 24]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425047/all/Porphyrins__Urine.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Porphyrins, Urine ID - 425047 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425047/all/Porphyrins__Urine PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -