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Coproporphyrin, porphobilinogen, urobilinogen, and other porphyrins.
To assess for porphyrins in the urine to assist with diagnosis of genetic disorders associated with porphyrin synthesis as well as heavy metal toxicity.
Urine from a random or timed specimen collected in a clean, amber-colored plastic collection container with sodium carbonate as a preservative.
(Method: High-performance liquid chromatography for porphyrins; spectrophotometry for δ-aminolevulinic acid and porphobilinogen)
|Test||Conventional Units||SI Units|
|(Conventional units × 1.53)|
|Coproporphyrin I||0–24 mcg/24 h||0–36.7 nmol/24 hr|
|Coproporphyrin III||0–74 mcg/24 hr||0–113.2 nmol/24 hr|
|(Conventional units × 1.43)|
|Uroporphyrins||0–24 mcg/24 hr||0–34.3 nmol/24 hr|
|(Conventional units × 1.34)|
|Hexacarboxylporphyrin||Less than 1 mcg/24 hr||Less than 1.34 nmol/24 hr|
|(Conventional units × 1.27)|
|Heptacarboxylporphyrin||Less than 4 mcg/24 hr||Less than 5.1 nmol/24 hr|
|(Conventional units × 4.42)|
|Porphobilinogen||Less than 2 mg/24 hr||Less than 8.8 micromol/24 hr|
|(Conventional units × 7.626)|
|δ-Aminolevulinic acid||1.5–7.5 mg/24 hr||11.4–57.2 micromol/24 hr|