Insulin and Insulin Response to Glucose

Insulin and Insulin Response to Glucose is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
N/A

Rationale
To assess the amount of insulin secreted in response to blood glucose to assist in diagnosis of types of hypoglycemia and insulin-resistant pathologies.

Patient Preparation
There are no fluid or activity restrictions unless by medical direction. If a single sample is to be collected, the patient should have fasted and refrained, with medical direction, from taking insulin or other oral hypoglycemic drugs for at least 8 hr before specimen collection. If serial specimens are to be collected, the patient should be prepared as for a standard oral glucose tolerance test over a 5-hr period. Protocols may vary among facilities.

Normal Findings
Method: Immunoassay.

75-g Glucose LoadInsulinSI Units (Conventional Units × 6.945)Tolerance for Glucose (Hypoglycemia)
FastingLess than 17 micro-international units/LLess than 118.1 pmol/LLess than 110 mg/dL
30 min6–86 micro-international units/L41.7–597.3 pmol/LLess than 200 mg/dL
1 hr8–118 micro-international units/L55.6–819.5 pmol/LLess than 200 mg/dL
2 hr5–55 micro-international units/L34.7–382 pmol/LLess than 140 mg/dL
3 hrLess than 25 micro-international units/LLess than 174 pmol/L65–120 mg/dL
4 hrLess than 15 micro-international units/LLess than 104.2 pmol/L65–120 mg/dL
5 hrLess than 8 micro-international units/LLess than 55.6 pmol/L65–115 mg/dL

Critical Findings and Potential Interventions
N/A

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