Protein, Blood, Total and Fractions
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Synonym/Acronym:
TP, SPEP (fractions include albumin, α1-globulin, α2-globulin, β-globulin, and γ-globulin).
Rationale
To assess nutritional status related to various disease and conditions such as dehydration, burns, and malabsorption.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
Method: Spectrophotometry for total protein, electrophoresis for protein fractions.
| Age | Conventional Units | SI Units (Conventional Units × 10) | |||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Newborn–5 days | 3.8–6.2 g/dL | 38–62 g/L | |||||||||||||||||||||||||||||||||||||||
| 1–3 yr | 5.9–7 g/dL | 59–70 g/L | |||||||||||||||||||||||||||||||||||||||
| 4–6 yr | 5.9–7.8 g/dL | 59–78 g/L | |||||||||||||||||||||||||||||||||||||||
| 7–9 yr | 6.2–8.1 g/dL | 62–81 g/L | |||||||||||||||||||||||||||||||||||||||
| 10–19 yr | 6.3–8.6 g/dL | 63–86 g/L | |||||||||||||||||||||||||||||||||||||||
| Adult | 6–8 g/dL | 60–80 g/L | |||||||||||||||||||||||||||||||||||||||
| Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms. | |||||||||||||||||||||||||||||||||||||||||
| Conventional Units | SI Units (Conventional Units × 10) | ||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Albumin | 3.4–4.8 g/dL | 34–48 g/L | |||||||||||||||||||||||||||||||||||||||
| α1-Globulin | 0.2–0.4 g/dL | 2–4 g/L | |||||||||||||||||||||||||||||||||||||||
| α2-Globulin | 0.4–0.8 g/dL | 4–8 g/L | |||||||||||||||||||||||||||||||||||||||
| β-Globulin | 0.5–1 g/dL | 5–10 g/L | |||||||||||||||||||||||||||||||||||||||
| .-Globulin | 0.6–1.2 g/dL | 6–12 g/L | |||||||||||||||||||||||||||||||||||||||
| Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms. | |||||||||||||||||||||||||||||||||||||||||
Critical Findings and Potential Interventions
N/A
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