Protein C

Protein C is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Protein C activity or protein C functional; protein C antigen.

Rationale
To assess coagulation function and assist in diagnosis of disorders such as thrombosis related to protein C deficiency.

Patient Preparation
There are no food, fluid, or activity restrictions unless by medical direction. Patients should discontinue warfarin therapy for 2 wk prior to specimen collection, as ordered. Specimen collection should not be performed sooner than 10 days following a thrombotic or clotting event.

Normal Findings


Protein C Activity or Functional Protein C (Method: Clot Detection)Protein C Antigen (Method: Enzyme Immunoassay)
70%–170%70%–140%
Values are significantly reduced in children because of liver immaturity. Levels rise to approximately 50% to 70% of adult levels by age 5 yr and reach adult levels by age 16 yr.

Critical Findings and Potential Interventions
N/A

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Synonym/Acronym:
Protein C activity or protein C functional; protein C antigen.

Rationale
To assess coagulation function and assist in diagnosis of disorders such as thrombosis related to protein C deficiency.

Patient Preparation
There are no food, fluid, or activity restrictions unless by medical direction. Patients should discontinue warfarin therapy for 2 wk prior to specimen collection, as ordered. Specimen collection should not be performed sooner than 10 days following a thrombotic or clotting event.

Normal Findings


Protein C Activity or Functional Protein C (Method: Clot Detection)Protein C Antigen (Method: Enzyme Immunoassay)
70%–170%70%–140%
Values are significantly reduced in children because of liver immaturity. Levels rise to approximately 50% to 70% of adult levels by age 5 yr and reach adult levels by age 16 yr.

Critical Findings and Potential Interventions
N/A

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