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Antithrombin III

Antithrombin III is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
Heparin cofactor assay, AT-III.

Common Use:
To assist in diagnosing heparin resistance or disorders resulting from a hypercoagulable state such as thrombus.

Specimen:
Plasma collected in a completely filled blue-top (3.2% sodium citrate) tube. If the patient’s hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted.

Normal Findings:
(Method: Chromogenic Immunoturbidimetric)

AT-III Activity
AgeConventional Units (% of Normal)
1–4 days39–87
5–29 days41–93
1–3 mo48–108
3–6 mo73–121
6–12 mo84–124
1–5 yr82–139
6–17 yr90–131
18 yr–older adult80–120
AT-III antigen
Newborn40–60
6 mo–Adult82–136

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Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Antithrombin III." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425209/all/Antithrombin_III.
Bladh ML, Van Leeuwen AM. Antithrombin III. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425209/all/Antithrombin_III. Accessed April 21, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Antithrombin III. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425209/all/Antithrombin_III
Bladh ML, Van Leeuwen AM. Antithrombin III [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 April 21]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425209/all/Antithrombin_III.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Antithrombin III ID - 425209 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425209/all/Antithrombin_III PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -