Antithrombin

General

Synonym/Acronym:
Antithrombin III, Antithrombin-heparin cofactor, AT, AT-III.

Rationale
To assist in diagnosing heparin resistance or disorders resulting from a hypercoagulable state such as thrombus.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Chromogenic for AT activity; Microlatex particle-mediated immunoassay for AT antigen.

AT Activity
AgeConventional Units (% of Normal)
Newborn39–87
Child82–139
Adult–older adult80–120
AT-III antigen
AgeConventional Units (% of Normal)
Newborn40–60
6 mo–adult82–136

Critical Findings and Potential Interventions
N/A

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