Davis's Lab & Diagnostic Tests
CD4/CD8 Enumeration and Viral Load Testing
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General
Synonym/Acronym:
T-cell profile, cell surface immunotyping.
Rationale
To monitor myeloproliferative diseases, immunodeficiency conditions, and HIV disease progression including the effectiveness of retroviral therapy.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
(Method: Flow cytometry) Results are not interchangeable from method to method. Therefore, it is important to use the same method for serial testing.
| Mature T Cells (CD3) | Helper T Cells (CD4) | Suppressor T Cells (CD8) | |||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Absolute (cells/microL) | Absolute (cells/microL) | Absolute (cells/microL) | |||||||||||||||||||||||||||||||||||||||
| Adult | 527–2,846 | 332–1,642 | 170–811 | ||||||||||||||||||||||||||||||||||||||
| CD4 cell counts are used for categorizing HIV infections, decision levels for initiating antiviral therapy, and to monitor efficacy of antiviral therapy. | |||||||||||||||||||||||||||||||||||||||||
Critical Findings and Potential Interventions
N/A
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General
Synonym/Acronym:
T-cell profile, cell surface immunotyping.
Rationale
To monitor myeloproliferative diseases, immunodeficiency conditions, and HIV disease progression including the effectiveness of retroviral therapy.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
(Method: Flow cytometry) Results are not interchangeable from method to method. Therefore, it is important to use the same method for serial testing.
| Mature T Cells (CD3) | Helper T Cells (CD4) | Suppressor T Cells (CD8) | |||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Absolute (cells/microL) | Absolute (cells/microL) | Absolute (cells/microL) | |||||||||||||||||||||||||||||||||||||||
| Adult | 527–2,846 | 332–1,642 | 170–811 | ||||||||||||||||||||||||||||||||||||||
| CD4 cell counts are used for categorizing HIV infections, decision levels for initiating antiviral therapy, and to monitor efficacy of antiviral therapy. | |||||||||||||||||||||||||||||||||||||||||
Critical Findings and Potential Interventions
N/A
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