Antibodies, Cardiolipin, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M

Antibodies, Cardiolipin, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
Antiphospholipid antibody, lupus anticoagulant, LA, ACA.

Common Use:
To detect the presence of antiphospholipid antibodies, which can lead to the development of blood vessel problems and complications including stroke, heart attack, and miscarriage.

Specimen:
Serum collected in a red-top tube.

Normal Findings:
(Method: Immunoassay, enzyme-linked immunosorbent assay [ELISA])

IgA (APL = 1 unit IgA phospholipid)IgG (GPL = 1 unit IgG phospholipid)IgM (MPL = 1 unit IgM phospholipid)
Negative: 0–11 APLNegative: 0–14 GPLNegative: 0–12 MPL
Indeterminate: 12–19 APLIndeterminate: 15–19 GPLIndeterminate: 13–19 MPL
Low-medium positive: 20–80 APLLow-medium positive: 20–80 GPLLow-medium positive: 20–80 MPL
Positive: Greater than 80 APLPositive: Greater than 80 GPLGreater than 80 MPL

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Citation

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TY - ELEC T1 - Antibodies, Cardiolipin, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M ID - 425258 Y1 - 2017 PB - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425258/all/Antibodies__Cardiolipin__Immunoglobulin_A__Immunoglobulin_G__and_Immunoglobulin_M ER -