Anticardiolipin Antibody, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M

Anticardiolipin Antibody, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Antiphospholipid antibody, lupus anticoagulant, LA, ACA.

Rationale
To detect the presence of antiphospholipid antibodies, which can lead to the development of blood vessel problems and complications including stroke, heart attack, and miscarriage.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Immunoassay, enzyme-linked immunosorbent assay (ELISA).

IgA (APL = 1 unit IgA phospholipid)IgG (GPL = 1 unit IgG phospholipid)IgM (MPL = 1 unit IgM phospholipid)
Negative: 0–11 APLNegative: 0–14 GPLNegative: 0–12 MPL
Indeterminate: 12–19 APLIndeterminate: 15–19 GPLIndeterminate: 13–19 MPL
Low-medium positive: 20–80 APLLow-medium positive: 20–80 GPLLow-medium positive: 20–80 MPL
Positive: Greater than 80 APLPositive: Greater than 80 GPLGreater than 80 MPL

Critical Findings and Potential Interventions
N/A

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Synonym/Acronym:
Antiphospholipid antibody, lupus anticoagulant, LA, ACA.

Rationale
To detect the presence of antiphospholipid antibodies, which can lead to the development of blood vessel problems and complications including stroke, heart attack, and miscarriage.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Immunoassay, enzyme-linked immunosorbent assay (ELISA).

IgA (APL = 1 unit IgA phospholipid)IgG (GPL = 1 unit IgG phospholipid)IgM (MPL = 1 unit IgM phospholipid)
Negative: 0–11 APLNegative: 0–14 GPLNegative: 0–12 MPL
Indeterminate: 12–19 APLIndeterminate: 15–19 GPLIndeterminate: 13–19 MPL
Low-medium positive: 20–80 APLLow-medium positive: 20–80 GPLLow-medium positive: 20–80 MPL
Positive: Greater than 80 APLPositive: Greater than 80 GPLGreater than 80 MPL

Critical Findings and Potential Interventions
N/A

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