Davis's Lab & Diagnostic Tests
Anticardiolipin Antibody, Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M
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Synonym/Acronym:
Antiphospholipid antibody, lupus anticoagulant, LA, ACA.
Rationale
To detect the presence of antiphospholipid antibodies, which can lead to the development of blood vessel problems and complications including stroke, heart attack, and miscarriage.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
Method: Immunoassay, enzyme-linked immunosorbent assay (ELISA).
| IgA (APL = 1 unit IgA phospholipid) | IgG (GPL = 1 unit IgG phospholipid) | IgM (MPL = 1 unit IgM phospholipid) |
|---|---|---|
| Negative: 0–11 APL | Negative: 0–14 GPL | Negative: 0–12 MPL |
| Indeterminate: 12–19 APL | Indeterminate: 15–19 GPL | Indeterminate: 13–19 MPL |
| Low-medium positive: 20–80 APL | Low-medium positive: 20–80 GPL | Low-medium positive: 20–80 MPL |
| Positive: Greater than 80 APL | Positive: Greater than 80 GPL | Greater than 80 MPL |
Critical Findings and Potential Interventions
N/A
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Synonym/Acronym:
Antiphospholipid antibody, lupus anticoagulant, LA, ACA.
Rationale
To detect the presence of antiphospholipid antibodies, which can lead to the development of blood vessel problems and complications including stroke, heart attack, and miscarriage.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
Method: Immunoassay, enzyme-linked immunosorbent assay (ELISA).
| IgA (APL = 1 unit IgA phospholipid) | IgG (GPL = 1 unit IgG phospholipid) | IgM (MPL = 1 unit IgM phospholipid) |
|---|---|---|
| Negative: 0–11 APL | Negative: 0–14 GPL | Negative: 0–12 MPL |
| Indeterminate: 12–19 APL | Indeterminate: 15–19 GPL | Indeterminate: 13–19 MPL |
| Low-medium positive: 20–80 APL | Low-medium positive: 20–80 GPL | Low-medium positive: 20–80 MPL |
| Positive: Greater than 80 APL | Positive: Greater than 80 GPL | Greater than 80 MPL |
Critical Findings and Potential Interventions
N/A
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