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Osmotic Fragility

Osmotic Fragility is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Red blood cell osmotic fragility, OF.

Rationale
To assess the fragility of erythrocytes related to red blood cell (RBC) lysis toward diagnosing diseases such as hemolytic anemia.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
(Method: Spectrophotometry) Hemolysis (unincubated) begins at 0.5% sodium chloride (NaCl) solution and is complete at 0.3% NaCl solution. Results are compared to a normal curve.

Critical Findings and Potential Interventions
N/A

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Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Osmotic Fragility." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility.
Bladh ML, Van Leeuwen AM. Osmotic Fragility. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility. Accessed July 19, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Osmotic Fragility. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility
Bladh ML, Van Leeuwen AM. Osmotic Fragility [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 July 19]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Osmotic Fragility ID - 425288 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -