Antiactin Antibody (Smooth Muscle) and Antimitochondrial M2 Antibody


Antiactin antibody, ASMA; mitochondrial M2 antibody, M2 antibody, AMA.

To assist in the differential diagnosis of chronic liver disease, typically biliary cholangitis.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Enzyme-linked immunosorbent (ELISA).

Actin smooth muscle antibody, IgG
NegativeLess than 20 units
Weak positive20–30 units
PositiveGreater than 30 units

Mitochondrial M2 antibody, IgG
NegativeLess than 20 units
Weak positive20.1–24.9 units
PositiveGreater than 25 units

Critical Findings and Potential Interventions

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