Lactate Dehydrogenase and Isoenzymes

Lactate Dehydrogenase and Isoenzymes is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
LDH and isos, LD, and isos.

Rationale
To assess myocardial or skeletal muscle damage toward diagnosing disorders such as myocardial infarction or damage to brain, liver, kidneys, and skeletal muscle.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
(Method: Enzymatic [L to P] for lactate dehydrogenase, electrophoretic analysis for isoenzymes) Reference ranges are method dependent and may vary among laboratories.


Lactate Dehydrogenase
AgeConventional and SI Units
0–2 yr125–275 units/L
2–3 yr166–232 units/L
4–6 yr104–206 units/L
7–12 yr90–203 units/L
13–14 yr90–199 units/L
15–43 yr90–156 units/L
Greater than 43 yr90–176 units/L
LDH Fraction% of TotalFraction of Total
LDH114–260.14–0.26
LDH229–390.29–0.39
LDH320–260.2–0.26
LDH48–160.08–0.16
LDH56–160.06–0.16

Critical Findings and Potential Interventions
N/A

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