Calcitonin and Calcitonin Stimulation Tests

Calcitonin and Calcitonin Stimulation Tests is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
Thyrocalcitonin.

Common Use:
To diagnose and monitor the effectiveness of treatment for medullary thyroid cancer.

Specimen:
Serum collected in a gold-, red-, or red/gray-top tube. Place separated serum in a plastic transport tube within 2 hr of collection.

Normal Findings:
(Method: Chemiluminescent immunoassay)

ProcedureMedication AdministeredRecommended Collection Times
Calcium and pentagastrin stimulationCalcium, 2 mg/kg IV for 1 min, followed by pentagastrin 0.5 mcg/kg4 calcitonin levels—baseline immediately before bolus; and 1 min, 2 min, and 5 min postbolus
Calcium stimulationCalcium, 2 mg/kg IV for 1 min or 2.4 mg/kg IV push4 calcitonin levels—baseline immediately before bolus; and 1 min, 2 min, and 5 min postbolus
Pentagastrin stimulationPentagastrin 0.5 mcg/kg4 calcitonin levels—baseline immediately before bolus; and 1 min, 2 min, and 5 min postbolus
IV = intravenous.
Conventional UnitsSI Units (Conventional Units × 1)
Calcitonin Baseline
 MaleLess than 10 pg/mLLess than 10 ng/L
 FemaleLess than 5 pg/mLLess than 5 ng/L
Maximum Response
5 min after calcium and pentagastrin stimulation
 Male8–343 pg/mL8–343 ng/L
 FemaleLess than 39 pg/mLLess than 39 ng/L
5 min after calcium stimulation
 MaleLess than 190 pg/mLLess than 190 ng/L
 FemaleLess than 130 pg/mLLess than 130 ng/L
5 min after pentagastrin stimulation
 MaleLess than 110 pg/mLLess than 110 ng/L
 FemaleLess than 30 pg/mLLess than 30 ng/L

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Citation

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TY - ELEC T1 - Calcitonin and Calcitonin Stimulation Tests ID - 425345 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425345/all/Calcitonin_and_Calcitonin_Stimulation_Tests PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -