Pseudocholinesterase and Dibucaine Number

Pseudocholinesterase and Dibucaine Number is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
CHS, PCHE, AcCHS.

Common Use:
To assess for pseudocholinesterase deficiency to assist in diagnosing a congenital deficiency. Special attention must be given to results for preoperative patients because positive results indicate risk for apnea with use of succinylcholine as an anesthetic drug.

Specimen:
Plasma collected in a lavender-top (EDTA) tube. Serum collected in a red-top tube is also acceptable.

Normal Findings:
(Method: Spectrophotometry, kinetic)

TestConventional Units
Pseudocholinesterase
 Males3,334–7,031 units/L
 Females2,504–6,297 inits/L
Dibucaine NumberFraction (%) of Activity Inhibited
Normal homozygote79%–84%
Heterozygote55%–70%
Abnormal homozygote16%–28%

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Citation

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TY - ELEC T1 - Pseudocholinesterase and Dibucaine Number ID - 425394 Y1 - 2017 PB - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425394/all/Pseudocholinesterase_and_Dibucaine_Number ER -