Pseudocholinesterase and Dibucaine Number
is a topic covered in the Davis's Lab & Diagnostic Tests
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CHS, PCHE, AcCHS.
To assess for pseudocholinesterase deficiency to assist in diagnosing a congenital deficiency. Special attention must be given to results for preoperative patients because positive results indicate risk for apnea with use of succinylcholine as an anesthetic drug.
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Method: Spectrophotometry, kinetic.
| Males||3,334–7,031 units/L|
| Females||2,504–6,297 inits/L|
|Dibucaine Number||Fraction (%) of Activity Inhibited|
Critical Findings and Potential Interventions
- A positive result indicates that the patient is at risk for prolonged or unrecoverable apnea related to the inability to metabolize succinylcholine. Notify the anesthesiologist if the test result is positive and surgery is scheduled.
Timely notification to the requesting health-care provider (HCP) of any critical findings and related symptoms is a role expectation of the professional nurse. A listing of these findings varies among facilities.
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Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Pseudocholinesterase and Dibucaine Number." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425394/all/Pseudocholinesterase_and_Dibucaine_Number.
Bladh ML, Van Leeuwen AM. Pseudocholinesterase and Dibucaine Number. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425394/all/Pseudocholinesterase_and_Dibucaine_Number. Accessed July 19, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Pseudocholinesterase and Dibucaine Number. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425394/all/Pseudocholinesterase_and_Dibucaine_Number
Bladh ML, Van Leeuwen AM. Pseudocholinesterase and Dibucaine Number [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 July 19]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425394/all/Pseudocholinesterase_and_Dibucaine_Number.
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A1 - Bladh,Mickey Lynn,
AU - Van Leeuwen,Anne M,
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