Gastric Analysis and Gastric Acid Stimulation Test

Gastric Analysis and Gastric Acid Stimulation Test is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
N/A

Rationale
To evaluate gastric fluid and the amount of gastric acid secreted toward diagnosing gastrointestinal disorders such as ulcers, cancers, and inflammation.

Patient Preparation
There are no activity restrictions unless by medical direction. Instruct the patient to fast from food after the evening meal the night before the test and not to drink water for 1 hr before the test. Instruct the patient to refrain from the use of chewing gum or tobacco products for at least 12 hr prior to and for the duration of the test. Drugs and substances that may alter gastric secretions (e.g., alcohol, histamine, nicotine, adrenocorticotropic steroids, insulin, parasympathetic drugs, belladonna alkaloids, anticholinergic drugs, histamine receptor antagonists) should be restricted by medical direction for 72 hr before the test. Protocols may vary among facilities.

Normal Findings
Method: Volume measurement and pH by ion-selective electrode.

Basal acid output (BAO)Male: 0–10.5 mmol/hr
Female: 0–5.6 mmol/hr
Peak acid output (PAO)Male: 12–60 mmol/hr
Female: 8–40 mmol/hr
Peak response timePentagastrin, intramuscular: 15–45 min
Pentagastrin, subcutaneous: 10–30 min
BAO/PAO ratioLess than 0.2

Critical Findings and Potential Interventions
N/A

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