Prion Disease Testing
is a topic covered in the Davis's Lab & Diagnostic Tests
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Transmissible spongiform encephalopathies, TSEs.
Testing for prion diseases may be considered for patients with undiagnosed, rapidly progressive dementia.
There are no activity restrictions unless by medical direction. Follow the food, fluid, or medication instructions indicated in the individual studies.
Negative biopsy, normal cerebrospinal fluid (CSF) protein levels, normal electroencephalogram (EEG), normal magnetic resonance imaging (MRI), normal neurologic examination.
- No evidence of prion disease
- Negative tonsillar biopsy (if variant Creutzfeldt-Jakob disease [vCJD] is being considered), as vCJD is the only type known to involve the lymph nodes, spleen, tonsil, and appendix. Note: A negative biopsy does not rule out vCJD.
Critical Findings and Potential Interventions
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Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Prion Disease Testing." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425453/all/Prion_Disease_Testing.
Bladh ML, Van Leeuwen AM. Prion Disease Testing. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425453/all/Prion_Disease_Testing. Accessed November 15, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Prion Disease Testing. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425453/all/Prion_Disease_Testing
Bladh ML, Van Leeuwen AM. Prion Disease Testing [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 November 15]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425453/all/Prion_Disease_Testing.
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