Antithyrotropin Receptor Antibodies: Binding Inhibition Antibodies and Stimulating Antibodies

Antithyrotropin Receptor Antibodies: Binding Inhibition Antibodies and Stimulating Antibodies is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Thyrotropin receptor antibodies, binding and stimulating: TSH receptor antibody (TRAb or TSHR); thyrotropin receptor binding antibody: thyrotropin-binding inhibitory immunoglobulin (TBII), TSH-binding inhibiting immunoglobulin; thyrotropin receptor stimulating antibody: long-acting thyroid stimulator (LATS), thyroid-stimulating immunoglobulins (TSI).

Rationale
To assist in diagnosing Graves disease related to thyroid function.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Electrochemiluminescent immunoassay for TBII and bioassay for TSI.

Thyrotropin Receptor Antibody (TRab)Thyroid-Stimulating Immunoglobulins (TSI)
Less than or equal to 1.75 units/LNegative (less than or equal to 122% basal activity)

Critical Findings and Potential Interventions
N/A

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Synonym/Acronym:
Thyrotropin receptor antibodies, binding and stimulating: TSH receptor antibody (TRAb or TSHR); thyrotropin receptor binding antibody: thyrotropin-binding inhibitory immunoglobulin (TBII), TSH-binding inhibiting immunoglobulin; thyrotropin receptor stimulating antibody: long-acting thyroid stimulator (LATS), thyroid-stimulating immunoglobulins (TSI).

Rationale
To assist in diagnosing Graves disease related to thyroid function.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Electrochemiluminescent immunoassay for TBII and bioassay for TSI.

Thyrotropin Receptor Antibody (TRab)Thyroid-Stimulating Immunoglobulins (TSI)
Less than or equal to 1.75 units/LNegative (less than or equal to 122% basal activity)

Critical Findings and Potential Interventions
N/A

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