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C18H24O2, a steroid produced by the ovary and possessing estrogenic properties. Large quantities are found in the urine of pregnant women and of mares and stallions, the latter two serving as sources of the commercial product that is used to treat estrogen deficiencies, e.g., menopause. Estradiol is effective when given subcutaneously or intramuscularly but not when given orally. It is converted to estrone in the body.
SEE: diethylstilbestrol; SEE: estrogen

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