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Azathioprine, basiliximab, cyclosporine, everolimus, mycophenolate, sirolimus, and tacrolimus are used with corticosteroids in the prevention of transplantation rejection reactions. Muromonab-CD3 is used to manage rejection reactions not controlled by other agents. Azathioprine, cyclophosphamide, and methotrexate are used in the management of selected autoimmune diseases (nephrotic syndrome of childhood and severe rheumatoid arthritis).