Testosterone, Total and Free

Testosterone, Total and Free is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
N/A

Rationale
To evaluate testosterone to assist in identification of disorders related to early puberty, late puberty, and infertility while assessing gonadal and adrenal function.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: HPLC/tandem MS for total and immunochemiluminometric assay (ICMA) for free testosterone.

Total Testosterone

Age	Conventional Units	SI Units (Conventional Units × 0.0347)
Newborn
Male	75–400 ng/dL	2.6–13.9 nmol/L
Female	16–44 ng/dL	0.56–1.53 nmol/L
1–5 mo
Male	Less than 300 ng/dL	Less than 10.41 nmol/L
Female	Less than 20 ng/dL	Less than 0.69 nmol/L
6–11 mo
Male	Less than 40 ng/dL	Less than 1.39 nmol/L
Female	Less than 9 ng/dL	Less than 0.31 nmol/L
1–5 yr
Male and female	Less than 20 ng/dL	Less than 0.69 nmol/L
6–7 yr
Male	Less than 20 ng/dL	Less than 0.69 nmol/L
Female	Less than 10 ng/dL	Less than 0.35 nmol/L
8–10 yr
Male	2–25 ng/dL	0.07–0.87 nmol/L
Female	1–30 ng/dL	0.04–1 nmol/L
11–12 yr
Male	Less than 350 ng/dL	Less than 12.1 nmol/L
Female	Less than 50 ng/dL	Less than 1.74 nmol/L
13–15 yr
Male	15–500 ng/dL	0.52–17.35 nmol/L
Female	Less than 50 ng/dL	Less than 1.74 nmol/L
Adult
Male	241–827 ng/dL	8.36–28.7 nmol/L
Female	15–70 ng/dL	0.52–2.43 nmol/L
Older adult
Male	300–720 ng/dL	10.41–24.98
Female	5–32 ng/dL	0.17–1.11
Post menopausal levels are about half the normal adult level for females; levels in women who are pregnant are three to four times the normal adult level for females who are not pregnant.

Free Testosterone

Age	Conventional Units	SI Units (Conventional Units × 3.47)
1–12 yr
Male and female	Less than 2 pg/mL	Less than 6.94 pmol/L
12–14 yr
Male	Less than 60 pg/mL	Less than 208 pmol/L
Female	Less than 2 pg/mL	Less than 6.94 pmol/L
14–18 yr
Male	4–100 pg/mL	13.88–347 pmol/L
Female	Less than 10 pg/mL	Less than 34.7 pmol/L
Adult
Male	50–224 pg/mL	173.5–777.28 pmol/L
Female	1–8.5 pg/mL	3.47–29.5 pmol/L
Older adult
Male	5–75 pg/mL	17.35–260.25 pmol/L
Female	1–8.5 pg/mL	3.47–29.5 pmol/L

Critical Findings and Potential Interventions
N/A

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