Davis's Lab & Diagnostic Tests
Metanephrines
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Synonym/Acronym:
N/A
Rationale
To assist in the diagnosis of cancer of the adrenal medulla or to assess for the cause of hypertension.
Patient Preparation
There are no food, fluid, or medication restrictions unless by medical direction. Instruct the patient to avoid excessive exercise and stress during the 24-hr collection of urine. Usually a 24-hr urine collection may be ordered. As appropriate, provide the required urine collection container and specimen collection instructions.
Normal Findings
Method: High-pressure liquid chromatography.
| Age | Conventional Units | SI Units |
|---|---|---|
| Normetanephrines | (Conventional Units × 5.07) | |
| 3 mo–4 yr | 54–249 mcg/24 hr | 274–1,262 micromol/day |
| 5–9 yr | 31–398 mcg/24 hr | 157–2,018 micromol/day |
| 10–17 yr | 67–531 mcg/24 hr | 340–2,692 micromol/day |
| 18–39 yr | 35–482 mcg/24 hr | 177–2,444 micromol/day |
| Greater than 40 yr | 88–676 mcg/24 hr | 446–3,427 micromol/day |
| Metanephrines, Total | (Conventional Units × 5.07) | |
| 3 mo–4 yr | 79–345 mcg/24 hr | 401–1,749 micromol/day |
| 5–9 yr | 49–409 mcg/24 hr | 248–2,074 micromol/day |
| 10–17 yr | 107–741 mcg/24 hr | 543–3,757 micromol/day |
| 18–39 yr | 94–695 mcg/24 hr | 477–3,524 micromol/day |
| 40–49 yr | 182–739 mcg/24 hr | 923–3,747 micromol/day |
| Greater than 50 yr | 224–832 mcg/24 hr | 1,136–4,218 micromol/day |
Critical Findings and Potential Interventions
N/A
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