Troponins I and T

General

Core Lab Study

Synonym/Acronym:
cardiac troponin, cardiac troponin I (cTnI), cardiac troponin T (cTnT).

Rationale
To assist in evaluating myocardial muscle damage related to disorders such as myocardial infarction (MI).

This Core Lab Study is considered the gold standard for identification of MI and has largely replaced the use of myoglobin and lactate dehydrogenase with isoenzymes.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Electrochemiluminescent immunoassay for troponin I, electrochemiluminescent immunoassay, fifth generation (high sensitivity) for troponin T.

Conventional UnitsSI Units (Conventional Units × 1)
Troponin I
Adult
MaleLess than or equal to 20 ng/LLess than or equal to 20 mcg/L
FemaleLess than or equal to 15 ng/LLess than or equal to 15 mcg/L
Troponin T (fifth generation)
Adult
MaleLess than or equal to 15 ng/LLess than or equal to 15 mcg/L
FemaleLess than or equal to 10 ng/LLess than or equal to 10 mcg/L
Normal values can vary significantly due to differences in test kit reagents and instrumentation. The testing laboratory should be consulted for comparison of results to the corresponding reference range.

Critical Findings and Potential Interventions
N/A

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