Mononucleosis Testing

General

Synonym/Acronym:
monospot, Epstein-Barr test, heterophil antibody test, IM serology.

Rationale
To assess for Epstein-Barr virus (EBV) and assist with diagnosis of infectious mononucleosis.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
(Method: Infectious mononucleosis antibodies (rapid IM) test by agglutination; serological tests for EBV early antigen D (IgG antibody), EBV nuclear antigen (IgG antibody), EBV viral capsid antigen (IgG antibody), EBV viral capsid antigen (IgM antibody) by immunoassay).

Rapid IM Negative (indicating nondetectable levels of the infectious mononucleosis heterophile antibody)
EBV antibody to early antigen D (IgG antibody) 10.9 Units/mL or less (EBV antibody to early antigen D, IgG antibody not detected)
EBV antibody to nuclear antigen (IgG antibody) 21.9 Units/mL or less (EBV antibody to nuclear antigen IgG not detected)
EBV antibody to viral capsid antigen (IgG antibody) 21.9 Units/mL or less (EBV antibody to viral capsid antigen IgG not detected)
EBV antibody to viral capsid antigen (IgM antibody) 43.9 Units/mL or less (EBV antibody to viral capsid antigen IgM not detected)


Critical Findings and Potential Interventions
N/A

There's more to see -- the rest of this topic is available only to subscribers.