Estradiol

General

Synonym/Acronym:
E2.

Rationale
To assist in diagnosing female fertility problems that may occur from tumor or ovarian failure.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Liquid chromatography/mass spectrometry.

AgeConventional UnitsSI Units (Conventional Units × 3.67)
12 mo–10 yr
  Male and femaleLess than 17 pg/mLLess than 62.4 pmol/L
11–15 yr
  MaleLess than 40 pg/mLLess than 147 pmol/L
  FemaleLess than 300 pg/mLLess than 1,100 pmol/L
Adult maleLess than 50 pg/mLLess than 184 pmol/L
Adult female
  Early follicular phase20–150 pg/mL73–551 pmol/L
  Late follicular phase40–350 pg/mL147–1,285 pmol/L
  Midcycle peak150–750 pg/mL551–2,753 pmol/L
  Luteal phase30–450 pg/mL110–1,652 pmol/L
  PostmenopauseLess than 20 pg/mLLess than 73 pmol/L
Levels for males and females are elevated at birth but decrease in a few days to prepubertal values. Levels vary significantly during the female menstrual cycle.

Critical Findings and Potential Interventions
N/A

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