Anticyclic Citrullinated Peptide Antibody

General

Synonym/Acronym:
Anti-CCP antibodies, ACPA.

Rationale
To assist in diagnosing rheumatoid arthritis and other rheumatic conditions.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
IgG Ab (Method: Enzyme-linked immunosorbent assay [ELISA]).

Anti-CCP antibodies
NegativeLess than 20 units
Weak positive20–39 units
Moderate positive40–59 units
Strong positive60 units or greater
14-3-3 eta proteinLess than 0.2 ng/mL

Critical Findings and Potential Interventions
N/A

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