General

Synonym/Acronym:
Acid hemolysis test for PNH.

Rationale
To assist in diagnosing a rare condition called paroxysmal nocturnal hemoglobinuria (PNH), wherein red blood cells (RBCs) undergo lysis during and after sleep with hemoglobin excreted in the urine.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
(Method: Acidified hemolysis) No hemolysis seen.

Critical Findings and Potential Interventions
N/A