Ham Test for Paroxysmal Nocturnal Hemoglobinuria
General
Synonym/Acronym:
Acid hemolysis test for PNH.
Rationale
To assist in diagnosing a rare condition called paroxysmal nocturnal hemoglobinuria (PNH), wherein red blood cells (RBCs) undergo lysis during and after sleep with hemoglobin excreted in the urine.
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
(Method: Acidified hemolysis) No hemolysis seen.
Critical Findings and Potential Interventions
N/A
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Citation
Van Leeuwen, Anne M., and Mickey Lynn. Bladh. "Ham Test for Paroxysmal Nocturnal Hemoglobinuria." Davis's Lab & Diagnostic Tests, 10th ed., F.A. Davis Company, 2023. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425119/all/Ham_Test_for_Paroxysmal_Nocturnal_Hemoglobinuria.
Van Leeuwen AMA, Bladh MLM. Ham Test for Paroxysmal Nocturnal Hemoglobinuria. Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2023. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425119/all/Ham_Test_for_Paroxysmal_Nocturnal_Hemoglobinuria. Accessed December 9, 2024.
Van Leeuwen, A. M., & Bladh, M. L. (2023). Ham Test for Paroxysmal Nocturnal Hemoglobinuria. In Davis's Lab & Diagnostic Tests (10th ed.). F.A. Davis Company. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425119/all/Ham_Test_for_Paroxysmal_Nocturnal_Hemoglobinuria
Van Leeuwen AMA, Bladh MLM. Ham Test for Paroxysmal Nocturnal Hemoglobinuria [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2023. [cited 2024 December 09]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425119/all/Ham_Test_for_Paroxysmal_Nocturnal_Hemoglobinuria.
* Article titles in AMA citation format should be in sentence-case
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T1 - Ham Test for Paroxysmal Nocturnal Hemoglobinuria
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AU - Van Leeuwen,Anne M,
BT - Davis's Laboratory & Diagnostic Tests
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