Biopsy, Bone Marrow is a topic covered in the Davis's Lab & Diagnostic Tests.

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Nursing Central

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General

Synonym/Acronym:
N/A

Common Use:
To assist in diagnosing hematological diseases and in identifying and staging myeloproliferative neoplasms and leukemias.

Specimen:
Bone marrow aspirate, bone core biopsy, marrow and peripheral smears.

Normal Findings:
(Method: Microscopic study of bone and bone marrow samples, flow cytometry) Reference ranges are subject to many variables, and therefore the laboratory should be consulted for their specific interpretation. Some generalities may be commented on regarding findings as follows:

  • Ratio of marrow fat to cellular elements is related to age, with the amount of fat increasing with increasing age.
  • Normal cellularity, cellular distribution, presence of megakaryocytes, and absence of fibrosis or tumor cells.
  • The myeloid-to-erythrocyte ratio (M:E) is 2:1 to 4:1 in adults. It may be slightly higher in children.
Differential ParameterConventional Units
Erythrocyte precursors18%–32%
Myeloblasts0%–2%
Promyelocytes2%–6%
Myelocytes9%–17%
Metamyelocytes7%–25%
Bands10%–16%
Neutrophils18%–28%
Eosinophils and precursors1%–5%
Basophils and precursors0%–1%
Monocytes and precursors1%–5%
Lymphocytes9%–19%
Plasma cells0%–1%

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Citation

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TY - ELEC T1 - Biopsy, Bone Marrow ID - 425120 Y1 - 2017 PB - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425120/all/Biopsy__Bone_Marrow ER -