d-Dimer

d-Dimer is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Dimer, fibrin degradation fragment.

Rationale
To assist in diagnosing a diffuse state of hypercoagulation as seen in disseminated intravascular coagulation (DIC), acute myocardial infarction (MI), deep venous thrombosis (DVT), and pulmonary embolism (PE).

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Immunoturbidimetric.

Conventional Units (FEU = Fibrinogen Equivalent Units)SI Units (Conventional Units × 5.476)
0–0.5 mcg/mL FEU0–2.7 nmol/L
Levels increase with age; the American College of Physicians recommends the use of age adjusted thresholds in patients more than 50 yr who have either a low or intermediate probability of PE using the formula age/100 where a 70-yr-old patient would have an age adjusted cutoff of 0.7 mcg/mL FEU.

Critical Findings and Potential Interventions
N/A

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Synonym/Acronym:
Dimer, fibrin degradation fragment.

Rationale
To assist in diagnosing a diffuse state of hypercoagulation as seen in disseminated intravascular coagulation (DIC), acute myocardial infarction (MI), deep venous thrombosis (DVT), and pulmonary embolism (PE).

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Immunoturbidimetric.

Conventional Units (FEU = Fibrinogen Equivalent Units)SI Units (Conventional Units × 5.476)
0–0.5 mcg/mL FEU0–2.7 nmol/L
Levels increase with age; the American College of Physicians recommends the use of age adjusted thresholds in patients more than 50 yr who have either a low or intermediate probability of PE using the formula age/100 where a 70-yr-old patient would have an age adjusted cutoff of 0.7 mcg/mL FEU.

Critical Findings and Potential Interventions
N/A

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