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δ-ALA, δ-aminolevulinic acid.
To assist in diagnosing lead poisoning in children, or porphyria, a disorder that disrupts heme synthesis, primarily affecting the liver.
There are no food, fluid, activity, or medication restrictions unless by medical direction. Usually, a 24-hr urine collection is ordered. As appropriate, provide the required urine collection container and specimen collection instructions.
|Conventional Units||SI Units (Conventional Units × 7.626)|
|1.5–7.5 mg/24 hr||11.4–57.2 micromol/24 hr|
Critical Findings and Potential Interventions
Signs and symptoms of an acute porphyria attack include pain (commonly in the abdomen, arms, and legs), nausea, vomiting, muscle weakness, rapid pulse, and high blood pressure. Possible interventions include medication for pain, nausea, and vomiting, and, if indicated, respiratory support. Initial treatment following a moderate to severe attack may include identification and cessation of harmful drugs the patient may be taking, IV infusion of glucose, and IV heme therapy (hematin, heme arginate) if indicated by markedly elevated urine δ-ALA and porphyrins.
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Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Delta-Aminolevulinic Acid." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425149/3/Delta_Aminolevulinic_Acid.
Bladh ML, Van Leeuwen AM. Delta-Aminolevulinic Acid. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425149/3/Delta_Aminolevulinic_Acid. Accessed September 19, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Delta-Aminolevulinic Acid. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425149/3/Delta_Aminolevulinic_Acid
Bladh ML, Van Leeuwen AM. Delta-Aminolevulinic Acid [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 September 19]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425149/3/Delta_Aminolevulinic_Acid.
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