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Protein, Blood, Total and Fractions

Protein, Blood, Total and Fractions is a topic covered in the Davis's Lab & Diagnostic Tests.

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General

Synonym/Acronym:
TP, SPEP (fractions include albumin, α1-globulin, α2-globulin, β-globulin, and γ-globulin).

Common Use:
To assess nutritional status related to various disease and conditions such as dehydration, burns, and malabsorption.

Specimen:
Serum collected in a gold-, red-, or red/gray-top tube.

Normal Findings:
(Method: Spectrophotometry for total protein, electrophoresis for protein fractions)


Total Protein
AgeConventional UnitsSI Units (Conventional Units × 10)
Newborn–5 d3.8–6.2 g/dL38–62 g/L
1–3 yr5.9–7 g/dL59–70 g/L
4–6 yr5.9–7.8 g/dL59–78 g/L
7–9 yr6.2–8.1 g/dL62–81 g/L
10–19 yr6.3–8.6 g/dL63–86 g/L
Adult6–8 g/dL60–80 g/L
Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms.

Protein Fractions
Conventional UnitsSI Units (Conventional Units × 10)
Albumin3.4–4.8 g/dL34–48 g/L
α1-Globulin0.2–0.4 g/dL2–4 g/L
α2-Globulin0.4–0.8 g/dL4–8 g/L
β-Globulin0.5–1 g/dL5–10 g/L
γ-Globulin0.6–1.2 g/dL6–12 g/L
Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms.

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Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Protein, Blood, Total and Fractions." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425180/all/Protein__Blood__Total_and_Fractions.
Bladh ML, Van Leeuwen AM. Protein, Blood, Total and Fractions. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425180/all/Protein__Blood__Total_and_Fractions. Accessed April 21, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Protein, Blood, Total and Fractions. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425180/all/Protein__Blood__Total_and_Fractions
Bladh ML, Van Leeuwen AM. Protein, Blood, Total and Fractions [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 April 21]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425180/all/Protein__Blood__Total_and_Fractions.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Protein, Blood, Total and Fractions ID - 425180 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425180/all/Protein__Blood__Total_and_Fractions PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -