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Chloride, Sweat

Chloride, Sweat is a topic covered in the Davis's Lab & Diagnostic Tests.

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Synonym/Acronym:
Sweat test, pilocarpine iontophoresis sweat test, sweat chloride.

Rationale
To assist in diagnosing cystic fibrosis (CF).

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Ion-specific electrode or titration.

Conventional and SI UnitsInterpretation
Birth–6 mo
0–29 mEq/L or mmol/LNormal
30–59 mEq/L or mmol/LBorderline
Greater than 60 mEq/L or mmol/LConsistent with the diagnosis of CF
6 mo–adult
0–39 mEq/L or mmol/LNormal
40–59 mEq/L or mmol/LBorderline
Greater than 60 mEq/L or mmol/LConsistent with the diagnosis of CF

Critical Findings and Potential Interventions

  • Greater than 60 mEq/L or mmol/L (SI greater than 60 mEq/L) is considered diagnostic of CF.

Timely notification to the requesting health-care provider (HCP) of any critical findings and related symptoms is a role expectation of the professional nurse. A listing of these findings varies among facilities

Consideration may be given to verification of critical findings before action is taken. Policies vary among facilities and may include requesting recollection and retesting by the laboratory.

The validity of the test result is affected tremendously by proper specimen collection and handling. Before proceeding with appropriate patient education and counseling, it is important to perform duplicate testing on patients whose results are in the diagnostic or intermediate ranges. A negative test should be repeated if test results do not support the clinical picture.

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Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Chloride, Sweat." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425208/3/Chloride_Sweat.
Bladh ML, Van Leeuwen AM. Chloride, Sweat. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425208/3/Chloride_Sweat. Accessed June 20, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Chloride, Sweat. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425208/3/Chloride_Sweat
Bladh ML, Van Leeuwen AM. Chloride, Sweat [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 June 20]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425208/3/Chloride_Sweat.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Chloride, Sweat ID - 425208 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425208/3/Chloride_Sweat PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -